Adriana Lepur

RESEARCH INTERESTS

Tissue development and compartmentalization
Advanced light microscopy
In vitro cell models
Protein engineering

EDUCATION

Ph.D. in Molecular Medicine  2012 – Double degree
Medical faculty, Lund University, Sweden
Faculty of Science, University of Zagreb, Croatia
M. Sc. in Pharmacy 2007
Faculty of Pharmacy and Biochemistry, University of Zagreb

PUBLICATIONS

Combining Unique Multiplex Gateway Cloning and Bimolecular Fluorescence Complementation (BiFC) for High-Throughput Screening of Protein-Protein Interactions.

Lepur A, Kovačević L, Belužić R, Vugrek O.

J Biomol Screen. 2016 Dec;21(10):1100-1111. doi: 10.1177/1087057116659438.

Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans.

Stegmayr J, Lepur A, Kahl-Knutson B, Aguilar-Moncayo M, Klyosov AA, Field RA, Oredsson S, Nilsson UJ, Leffler H.

J Biol Chem. 2016 Jun 17;291(25):13318-34. doi: 10.1074/jbc.M116.721464.

Ligand induced galectin-3 protein self-association.

Lepur A, Salomonsson E, Nilsson UJ, Leffler H.

J Biol Chem. 2012 Jun 22;287(26):21751-6. doi: 10.1074/jbc.C112.358002.

Galectin-3 endocytosis by carbohydrate independent and dependent pathways in different macrophage like cell types.

Lepur A, Carlsson MC, Novak R, Dumić J, Nilsson UJ, Leffler H.

Biochim Biophys Acta. 2012 Jul;1820(7):804-18. doi: 10.1016/j.bbagen.2012.02.018.

Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.

Carlsson MC, Cederfur C, Schaar V, Balog CI, Lepur A, Touret F, Salomonsson E, Deelder AM, Fernö M, Olsson H, Wuhrer M, Leffler H.

PLoS One. 2011;6(10):e26560. doi: 10.1371/journal.pone.0026560.

SPECIALISED COURSES

Statistics in Medicine
Writing in the Sciences
Scientific and oral communication
Research ethics
Glycobiology